Protein Details: Gap junction beta-6 protein

Protein ID

ICDB_Pro_0287

Protein Name

Gap junction beta-6 protein

Gene Name

GJB6

Organism

Gallus gallus (Chicken)

Length

263 amino acids

AlphaFoldDB

AF-O93533-F1-model_v4.pdb

Function

Sequence

MDWGALQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAERVWGDEQDDFICNTLQPGCKNVCYDHFFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRQFRKGDQKCEYKDIEEIRTQRFRIEGTLWWTYTCSIFFRLVFEAVFMYAFYFMYDGFRMPRLMKCSAWPCPNTVDCFVSRPTEKTVFTIFMIAVSSICILLNVAELCYLLTKFFLRRSRKAGNQKHHPNHENKEETKQNEMNELISDSCQNTVIGFTSS

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Exclusively expressed in the cochlea of the inner ear; where it is found in cells of the tegmentum vasculosum; cuboidal cells; supporting cells and clear cells

DOI ID

10.1073/pnas.95.19.11400

RefSeq

NP_990262.1; XP_015133175.1; XP_015133180.1; XP_015133186.1